AC-262,536
The preparation contributes to the building of lean muscle mass, increases the synthesis of muscle proteins, strength and training endurance. Additional benefits of using the product are a healthy prostate and increased sexual performance. Accadrine also accelerates fat loss.
It has a beneficial effect on the prostate gland because it can strongly antagonize the action of dihydroxytestosterone (DHT). Compound It does not affect the body's hormonal balance and is a safe method for the development of muscles.
NAC - is an organic compound which is an acetyl derivative of cysteine - an endogenous sulfuric amino acid that occurs naturally in our body and in food proteins. It takes part in the synthesis of proteins, enzymes are part of structural proteins. L-cysteine, in combination with glutamine and glycine, is essential in the synthesis of glutathione (GSH) - one of the most important antioxidants in our body.
Rosmarinic Acid - rosmarinic acid - has anti-inflammatory and antioxidant effects on the body. It is also an inhibitor of enzymes responsible for the breakdown of hyaluronic acid, which conditions the elasticity and youth of the skin by retaining water in it.
Vitamin E - has many different functions. It stands right next to vitamins A and C, as all of them are powerful antioxidants designed to protect the body against oxidative stress and cell damage caused by free radicals. In addition, vitamin E inhibits the oxidation of LDL cholesterol, thus preventing the formation of atherosclerotic plaque. It takes an active part in the synthesis of anticoagulants, maintaining the proper permeability of cell membranes and minimizes the phenomenon of clumping of platelets, therefore it effectively prevents the formation of clots in blood vessels. It is recommended for people with high blood cholesterol levels. It can be used in the prophylaxis against myocardial infarction. The research carried out so far has shown that vitamin E has an anti-cancer effect.
AC-262,536 - the compound belongs to the so-called A SARM that acts as a selective androgen receptor modulator. AC-262536 interacts with androgen receptors in bone and muscle. Unlike other SARMs, AC-262,536 binds directly to the androgen receptor. As a result, it activates the androgen receptor, especially in the cells that make up bone and muscles, without reducing libido. AC-262536 is mainly used for the development of dry and hard muscle mass. Compared to testosterone, AC-262,536 increases muscle growth by as much as 66% without the negative side effects. Studies show that AC-262536 can bind to androgen receptors and inhibit luteinizing hormone (LH) much more strongly than testosterone alone.
Dosage:
1 capsule 3 times a day before meals{Drugbox
| verifiedrevid = 448229525
| IUPAC_name = 4-[(1R,3S,5S)-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl]naphthalene-1-carbonitrile
| image = AC-262,356.svg
| width = 250px
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| CAS_number = 870888-46-3
| CAS_supplemental =
871032-12-1 (exo form)
| ATC_prefix =
| ATC_suffix =
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| UNII = U8VS41J5O6
| ChemSpiderID = 31129035
| ChEMBL = 3084525
| C=18 | H=18 | N=2 | O=1
| SMILES = OC1C[C@@H]2CC[C@H](C1)N2c3ccc(C#N)c4ccccc34
| StdInChI = 1S/C18H18N2O/c19-11-12-5-8-18(17-4-2-1-3-16(12)17)20-13-6-7-14(20)10-15(21)9-13/h1-5,8,13-15,21H,6-7,9-10H2/t13-,14+,15+
| StdInChIKey = ATKWLNSCJYLXPF-FICVDOATSA-N
}}
AC-262536 is a drug developed by Acadia Pharmaceuticals which acts as a selective androgen receptor modulator (SARM). Chemically it possesses endo-exo isomerism, with the endo form being the active form. It acts as a partial agonist for the androgen receptor with a Ki of 5nM, and no significant affinity for any other receptors tested. In animal studies it produced a maximal effect of around 66% of the anabolic action of testosterone, but only around 27% of its potency as an androgen.[1]
References
- Piu F, Gardell LR, Son T, Schlienger N, Lund BW, Schiffer HH, et al. (March 2008). "Pharmacological characterization of AC-262536, a novel selective androgen receptor modulator". The Journal of Steroid Biochemistry and Molecular Biology. 109 (1–2): 129–37. doi:10.1016/j.jsbmb.2007.11.001. PMID 18164613. S2CID 25172405.
AC-262,536 - the compound belongs to the so-called A SARM that acts as a selective androgen receptor modulator. AC-262536 interacts with androgen receptors in bone and muscle. Unlike other SARMs, AC-262,536 binds directly to the androgen receptor. As a result, it activates the androgen receptor, especially in the cells that make up bone and muscles, without reducing libido. AC-262536 is mainly used for the development of dry and hard muscle mass. Compared to testosterone, AC-262,536 increases muscle growth by as much as 66% without the negative side effects. Studies show that AC-262536 can bind to androgen receptors and inhibit luteinizing hormone (LH) much more strongly than testosterone alone.