Trypanosoma congolense

Trypanosoma congolense is a species of trypanosomes and is the major pathogen responsible for the disease nagana in cattle and other animals including sheep, pigs, goats, horses and camels, dogs,[1] as well as laboratory mice. It is the most common cause of nagana in east Africa, but is also a major cause of nagana in west Africa. This parasite is spread by tsetse flies. In its mammalian host, Trypanosoma congolense only lives in blood vessels, and causes in particular anaemia.[1][2][3]

  • Cachectic dog infested with Trypanosoma congolense after a travel in West Africa

Trypanosoma congolense
Scientific classification
Domain:
Eukaryota
(unranked):
Excavata
Phylum:
Euglenozoa
Class:
Kinetoplastida
Order:
Trypanosomatida
Family:
Trypanosomatidae
Genus:
Trypanosoma
Species:
T. congolense
Binomial name
Trypanosoma congolense
Broden, 1904

Drug resistance

Individuals isolated from Boran cattle in the Gibe River Valley in southwest Ethiopia showed universal resistance between July 1989 and February 1993.[4] This likely indicates a permanent loss of function in this area for the tested trypanocides, Diminazene aceturate, Isometamidium chloride, and Homidium chloride.[4]

References
  1. Deschamps, Jack-Yves; Desquesnes, Marc; Dorso, Laetitia; Ravel, Sophie; Bossard, Géraldine; Charbonneau, Morgane; Garand, Annabelle; Roux, Françoise A. (2016). "Refractory hypoglycaemia in a dog infected with Trypanosoma congolense". Parasite. 23: 1. doi:10.1051/parasite/2016001. ISSN 1776-1042. PMC 4722231.
  2. Losos, G. J.; Ikede, B. O. (1972). "Review of pathology of diseases in domestic and laboratory animals caused by Trypanosoma congolense, T. vivax, T. brucei, T. rhodesiense and T. gambiense". Veterinary Pathology. 9 (1 Suppl): 1–79. doi:10.1177/030098587200901s01. ISSN 0300-9858.
  3. African Animal Trypanosomiasis Archived 2007-02-13 at the Wayback Machine, USAHA gray book, 6th ed. (1998).
  4. Mulugeta, Wubet; Wilkes, Jon; Mulatu, Woudyalew; Majiwa, Phelix A.O; Masake, Rachael; Peregrine, Andrew S (1997). "Long-term occurrence of Trypanosoma congolense resistant to diminazene, isometamidium and homidium in cattle at Ghibe, Ethiopia". Acta Tropica. Elsevier BV. 64 (3–4): 205–217. doi:10.1016/s0001-706x(96)00645-6. ISSN 0001-706X. PMID 9107367. S2CID 23878484.

Media related to Trypanosoma congolense at Wikimedia Commons

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.