Acefylline

Acefylline (INN),[1] also known as acetyloxytheophylline, is a stimulant drug of the xanthine chemical class. It acts as an adenosine receptor antagonist. It is combined with diphenhydramine in the pharmaceutical preparation etanautine to help offset diphenhydramine induced drowsiness.[2]

Acefylline
Clinical data
ATC code
Identifiers
IUPAC name
  • (1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetic acid
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.010.447
Chemical and physical data
FormulaC9H10N4O4
Molar mass238.203 g·mol−1
3D model (JSmol)
SMILES
  • O=C2N(c1ncn(c1C(=O)N2C)CC(=O)O)C
InChI
  • InChI=1S/C9H10N4O4/c1-11-7-6(8(16)12(2)9(11)17)13(4-10-7)3-5(14)15/h4H,3H2,1-2H3,(H,14,15) Y
  • Key:HCYFGRCYSCXKNQ-UHFFFAOYSA-N Y
  (verify)

See also

References
  1. "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names (Rec. INN): List 21" (PDF). World Health Organization. Retrieved 29 December 2016.
  2. Zuidema J (1978). "Biofarmaceutische en farmacokinetische aspecten van theofylline en acefylline". Thesis (doctoral)--Universiteit van Amsterdam. Archived from the original on 2016-12-30. Retrieved 2012-09-29. Cite journal requires |journal= (help)
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