Ethinylestradiol/drospirenone
Ethinylestradiol/drospirenone (EE/DRSP), sold under the brand name Yasmin among others, is a combination of ethinylestradiol (EE), an estrogen, and drospirenone (DRSP), a progestin, antimineralocorticoid, and antiandrogen, which is used as a birth control pill to prevent pregnancy in women.[2][3][4][5] It is also indicated for the treatment of moderate acne, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), and dysmenorrhea (painful menstruation) in women.[3] The medication is taken by mouth and contains 30 μg EE and 3 mg DRSP per tablet (brand names Yasmin, others) or 20 μg EE and 3 mg DRSP per tablet (brand names Yaz, Yasminelle, Nikki, others).[4][5] A formulation with levomefolic acid (vitamin B9) has also been marketed (brand names Beyaz, Safyral, others), with similar indications.[6][7] EE/DRSP is marketed widely throughout the world.[8]
 Ethinylestradiol | |
 Drospirenone | |
| Combination of | |
|---|---|
| Ethinylestradiol | Estrogen |
| Drospirenone | Progestogen; Progestin; Antimineralocorticoid; Antiandrogen |
| Clinical data | |
| Trade names | With 30 μg ethinylestradiol: Yasmin, others With 20 μg ethinylestradiol: Yaz, Yasminelle, others |
| Other names | EE/DRSP |
| AHFS/Drugs.com | Professional Drug Facts |
| MedlinePlus | a601050 |
| License data | |
| Pregnancy category |
|
| Routes of administration | By mouth |
| Drug class | Estrogen; Progestin; Progestogen; Antimineralocorticoid; Antiandrogen |
| ATC code | |
| Legal status | |
| Legal status |
|
| Identifiers | |
| CAS Number | |
| KEGG | |
In 2017, it was the 98th most commonly prescribed medication in the United States, with more than eight million prescriptions.[9][10]
See also
References
- "Drospirenone / estradiol (Angeliq) Use During Pregnancy". Drugs.com. 6 September 2018. Retrieved 18 March 2020.
- https://adisinsight.springer.com/drugs/800007379
- https://adisinsight.springer.com/drugs/800017043
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021098s028lbl.pdf
- "Yaz" (PDF). Retrieved October 31, 2017.
- https://adisinsight.springer.com/drugs/800032716
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022532s001lbl.pdf
- https://www.drugs.com/international/drospirenone.html
- "The Top 300 of 2020". ClinCalc. Retrieved 11 April 2020.
- "Drospirenone; Ethinyl Estradiol - Drug Usage Statistics". ClinCalc. Retrieved 11 April 2020.
External links
- "Drospirenone mixture with estradiol". Drug Information Portal. U.S. National Library of Medicine.
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