Felbinac

Felbinac (INN, or biphenylylacetic acid) is a topical medicine, belonging to the family of medicines known as nonsteroidal anti-inflammatory drugs (NSAIDs) of the arylacetic acid (not arylpropionic acid) class, which is used to treat muscle inflammation and arthritis. It is an active metabolite of fenbufen.[1]

Felbinac
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Topical
ATC code
Legal status
Legal status
Identifiers
IUPAC name
  • biphenyl-4-ylacetic acid
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.024.758
Chemical and physical data
FormulaC14H12O2
Molar mass212.248 g·mol−1
3D model (JSmol)
SMILES
  • O=C(O)Cc1ccc(cc1)c2ccccc2
InChI
  • InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16) Y
  • Key:QRZAKQDHEVVFRX-UHFFFAOYSA-N Y
  (verify)

See also
  • The isopropyl acid is called Biprofen (cf Flurbiprofen) and is used to prepare Bifepramide.
  • The α-ethyl acid is called Xenbucin, this in turn is used to make Xenthiorate.
  • Xenyhexenic Acid
  • Fluenetil

Footnotes
  1. Kohler C, Tolman E, Wooding W, Ellenbogen L (1980). "A review of the effects of fenbufen and a metabolite, biphenylacetic acid, on platelet biochemistry and function". Arzneimittelforschung. 30 (4A): 702–707. PMID 6254545.

References
  • The Merck Index, 12th Edition. 3989
  • Description of Felbinac on Tiscali


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.