Phenbenzamine

Phenbenzamine (Antergan) is an antihistamine with anticholinergic properties.[1]

Phenbenzamine
Clinical data
Trade namesAntergan
Identifiers
IUPAC name
  • N-(2-Dimethylaminoethyl)-N-benzylaniline
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H22N2
Molar mass254.377 g·mol−1
3D model (JSmol)
SMILES
  • CN(C)CCN(Cc1ccccc1)c2ccccc2
InChI
  • InChI=InChI=1S/C17H22N2/c1-18(2)13-14-19(17-11-7-4-8-12-17)15-16-9-5-3-6-10-16/h3-12H,13-15H2,1-2H3 Y
  • Key:CHOBRHHOYQKCOU-UHFFFAOYSA-N Y

Synthesis
Phenbenzamine synthesis:[2][3]
Antergan thienyl analog

See also

References
  1. "Phenbenzamine". Encyclopædia Britannica.
  2. US 2634293, Kyrides LP, Zienty FB, "Process of preparing a monobasic salt of a secondary amine", issued 7 April 1953, assigned to Monsanto Chemicals
  3. Kaye IA, Parris CL, Weiner N (1953). "A Novel N-Alkylation Reaction". Journal of the American Chemical Society. 75 (3): 744–745. doi:10.1021/ja01099a508.


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