Amdoxovir

Amdoxovir is a nucleoside reverse transcriptase inhibitor (NRTI) undergoing research for the treatment of HIV/AIDS. It was discovered by Raymond F. Schinazi (Emory University) and C.K. Chu (University of Georgia). It is being developed by RFS Pharma.[1] Currently, it is in Phase II clinical studies.

Amdoxovir
Clinical data
ATC code
  • none
Identifiers
IUPAC name
  • [(2R,4R)-4-(2,6-diaminopurin-9-yl)-1,3-dioxolan-2-yl]methanol
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
NIAID ChemDB
Chemical and physical data
FormulaC9H12N6O3
Molar mass252.234 g·mol−1
3D model (JSmol)
SMILES
  • n2c1c(nc(nc1n(c2)[C@@H]3O[C@@H](OC3)CO)N)N
InChI
  • InChI=1S/C9H12N6O3/c10-7-6-8(14-9(11)13-7)15(3-12-6)4-2-17-5(1-16)18-4/h3-5,16H,1-2H2,(H4,10,11,13,14)/t4-,5-/m1/s1 Y
  • Key:RLAHNGKRJJEIJL-RFZPGFLSSA-N Y
  (verify)

References

  1. "Amdoxovir". AIDSmeds.com. January 13, 2009. Archived from the original on 2008-03-21. Retrieved March 21, 2008.


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